Abstract:Objective: To understand and analyze the problems existing in the recruitment of voluntary blood donor in Anhui Province, so as to provide evidence for targeted intervention in blood donation and the formulation of recruitment strategies. Methods: We used a self-designed questionnaire to investigate the blood donors in three cities from middle, northern, and southern Anhui Province. Three blood sampling points were randomly selected in the three cities, and data were collected for data analysis. Results: A total of 583 street donors were surveyed, 250 in middle Anhui, 105 in southern Anhui, and 228 in northern Anhui. The number of first-time blood donors were 255 (43.7%), and 294 (50.4%) were repeated blood donors. Blood donation policy witting rate was 52.3%, and knowledge witting rate was 71.4%. Repeated blood donors offer the relevant knowledge to master the degree (72.6%) was higher than first-time blood donors (70.1%). The factors affecting donor repeat blood donation were regional differences, occupational differences, and whether their family members donate blood. Most of the donors who do not want to repeat blood donation were afraid of pain and fear of infectious diseases. Conclusion: The knowledge-attitude-practice of volunteer blood donors in Anhui Province should be improved. At the same time, in order to consolidate and retain existing blood donors, we should improve the incentive mechanism of blood donation and the propaganda of health benefit of blood donation to provide adequate protection for the clinical use of blood.