Objective: To investigate the status of hypertension compliance as well as their influence factors in hypertensive rural residents of Lianyungang so as to provide evidences for the prevention and treatment. Methods: With two-stage sampling, 1 306 hypertensive patients with antihypertensive medication from Lianyungang were surveyed with a general data questionnaire and the Morisky adherence questionnaire (MAQ). Univariate χ2 test and binary logistic regression model were used to analyze all kinds of key factors. Results: The compliance of patients with hypertension was 27.8%. The logistic regression analysis showed that the main effect factors influencing the compliance were gender, age, degree of education, career, monthly income, marital status, family history of hypertension and course of disease. Conclusion: The rate of compliance is relatively low in rural areas of Lian Yungang. Hypertension treatment should consider all factors and take the right intervention measures to improve the compliance of patients with hypertension.