Before the founding of new China, the "family standard?interpersonal trust" model prevailed in China for a long time, and the trust between doctors and patients was naturally established and passed on from generation to generation. In the early period of new China, under the condition that the "national standard?system trust" model gradually became the social leading trust mode, the trust between doctors and patients, although has changed a little, basically maintained the state of historical continuity and stationary reconstruction. Since China’s reform and opening up, the trust between doctors and patients has fallen into the dilemma. In the new period, we must promote the social trust model to realize the double transition, namely from the emotional trust transition to institutional trust, and then from institutional trust to cultural transition ,so that we can break the doctor?patient trust dilemma with the combination of rigid institutional constraints and flexible cultural nourishment.