Objective： To understand the working pressure of medical personnel in small private medical institutions, analyze their influencing factors, provide reference for alleviating the working pressure of medical personnel, in order to improve their quality of life and reduce their turnover rate. Methods: Descriptive statistics, chi?square test and ordinal regression were used to analyze the working pressure and influencing factors of medical staff. Results: A total of 91.79% of the respondents felt that the work had a lot of personal capacity requirements; 68.13% of the respondents thought that the work tension was high; 55.84% of the medical staff worked longer than the statutory working hours （40 hours） per week; 72.39% of the medical staff felt high pressure of work. Weekly working hours and job stress were the main influencing factors of working pressure for medical staff. Conclusion: Small private medical institutions should set up a training platform for medical personnel training, reasonable arrangements for medical staff working hours, provide a comfortable working environment, recruit more and better technical personnel, encourage existing medical staff to improve work efficiency, strengthen mental health of the publicity and education. Medical staff should be positive, optimistic response to work pressure, integrate into the hospital work and life.