Based on modern hospital management system, analyzing the current situation of human resource management system in maternal and child health hospital,summarizing the existing problems,and putting forward the corresponding suggestions. The following problems existed in the human resource management of maternal and child health hospital: the shortage of talents was serious, the health function needed to be strengthened, the reform of personnel system was slow, and the salary system was unreasonable. Based on the modern hospital management system, combined with the existing problems, we should promote the construction and improvement of human resource management system in maternal and child health hospital by accelerating system reform, innovate the talent introduction and training means, pay attention to clinical and health care, and build a reasonable salary system to promote the improvement of human resource management system in modern maternal and child health hospital.