体外循环先心手术甲状腺功能减退及替代治疗
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南京医科大学附属儿童医院心胸外科

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Hypothyroidism and replacement therapy after surgery for congenital heart disease with cardiopulmonary bypass
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    摘要:

    先天性心脏病被认为和甲状腺激素密切相关,经过体外循环的先心手术可导致甲状腺激素显著降低,而甲状腺功能减退亦可影响心脏术后康复。术后甲状腺激素替代治疗虽作为一种可行的方法,但目前尚没有明确的证据能够表明它的价值,且心脏手术后常规应用甲状腺激素纠正儿童正常甲状腺病态综合征(Euthyroid sick syndrome, ESS)的方法尚未建立。本文通过阐述先天性心脏病与甲状腺功能减退的关系,来初步探讨甲状腺激素替代治疗的可行性。

    Abstract:

    Congenital heart disease is thought to be closely related to thyroid hormones,surgery for congenital heart disease with cardiopulmonary bypass can lead to a significant decrease in thyroid hormones, and hypothyroidism can also affect recovery from heart surgery.Postoperative thyroid hormone replacement therapy as a feasible method, it does not provide clear evidence of the value of thyroid hormone therapy,the routine application of thyroid hormone after cardiac surgery to correct Euthyroid sick syndrome (ESS) in children has not been established. This paper discusses the relationship between congenital heart disease and hypothyroidism to explore the feasibility of thyroid hormone replacement therapy.

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  • 收稿日期:2020-08-26
  • 最后修改日期:2020-12-11
  • 录用日期:2021-06-21
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