Objective: To analyze the epidemiological characteristics of the outbreak caused by severe acute respiratory syndrome coronavirus 2 （SARS-CoV-2）Delta variant in Jiangsu Province and to provide scientific basis for epidemic prevention and control. Methods:?The coronavirus disease 2019（COVID-19）data, reported?from?July?20?to?August?28?in?Jiangsu Province, such as basic information, epidemiological history, date of diagnosis, was collected for statistical descriptive analysis. Results: During periods?of?investigation?time, there were 820 cases in Jiangsu Province, and the fatality rate was 0. 341 cases （41.6%）were male. The median age was 48 years. At the time of diagnosis, differences of the median age between mild, moderate and severe cases were statistically significant (P<0.05). The median incubation period was 9.5 (7.5, 11) days. The median serial interval was 3 (2, 5) days. Differences in serial intervals between 1st to 2nd and 2nd to 3rd generation were statistically significant (P<0.001), 2nd to 3rd and 3rd to 4th generation were statistically significant (P<0.05). The sensitivity of the first nucleic acid testing was 77.7%. Conclusion: The SARS-CoV-2 Delta variant is with high transmissibility and spreads rapidly. All age groups are susceptible the Delta variant, and the age was trending younger. Severe cases are more likely to occur in the elderly. Multiple nucleic acid tests are recommended for patients with fever, cough and other symptoms in medium-high risk areas.