Objective: To investigate the effect of intravenous lidocaine on tourniquet-related hypertension (TIH) under general anesthesia. Methods: We selected 40 patients with ASA I or II grade undergoing ambulatory knee arthroscopy surgery in our hospital. The patients were divided into two groups randomly : the control group (group C) and the lidocaine group (group L). Patients in the lidocaine group were given a load of 1.0 mg/kg for 15 minutes after induction and then maintained at 1.0 mg/kg/h until the end of the operation. The control group was treated with the same volume of saline . Index including HR, SBP, DBP, MAP were observed at these times：after entering the room (T0 ), 5 min after induction (T1 ), the time when tourniquet is inflated (T2), 30 min after tourniquet is inflated (T3 ), 45 min after tourniquet is inflated (T4 ), 60 min after tourniquet is inflated (T5 ), before deflation (T6 ), 20 min after tourniquet is deflated (T7); Recording the occurrence of tourniquet-related hypertension (TIH) and the use of antihypertensive drugs; Recording the resting VAS scores at 1, 3, 6, 24, and 48 hours after surgery; Recording the occurrence of adverse reactions such as local anesthetic poisoning.Results: In the C group and the L group, the differences in hemodynamics measured at different time points are statistically different (P<0.001). Compared to these at T2, blood pressure and heart rate at T3, T4, T5, and T6 showed an upward trend. At T3, T4, T5, and T6, BP in the L group was lower than that in the C group (all P<0.05). At T4 and T5, HR of the L group was lower than that in the C group. At T3 and T4, the incidence of TIH in the L group was lower than that in C group (P=0.008; P=0.011). Compared to the C group, the L group had lower VAS scores at 1h, 3h, and 6h after surgery (P=0.023; P=0.025; P=0.03). There was no statistical difference between the two groups at other time points. Conclusion: In knee arthroscopic surgery using tourniquets, low-dose intravenous lidocaine can effectively prevent tourniquet-related hypertension (TIH) and improve the quality of postoperative rehabilitation.