新型冠状病毒无症状感染者占比特征研究
DOI:
作者:
作者单位:

1.南京医科大学公共卫生学院;2.无锡市疾病预防控制中心;3.南京医科大学附属无锡疾病预防控制中心

作者简介:

通讯作者:

中图分类号:

基金项目:

无锡市卫生健康委项目(BJ2020100),无锡市卫健委重大项目(Z202019),无锡市科技局发展项目(Y20212042),无锡市卫健委医学重点学科项目(FZXK202110)


A Study on The proportion of Asymptomatic Infections of Novel Coronavirus
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的 为了客观、科学的描述无症状感染者在新冠病毒感染谱中的流行病学特征。方法 检索PubMed、中国知网以及万方数据库中公开发表的文章,限定搜索词,检索时间截至2022年3月,并对纳入的研究使用R version 4.1.3软件进行Meta分析。结果 共纳入53项研究,SARS-CoV-2感染者中无症状感染者占比为28.47%(95%CI:22.05%,35.9%)。Meta亚组分析表明,不同年龄和毒株类型中SARS-CoV-2无症状感染者占比在组间差异有统计学意义;而在不同地区(大洲)、职业、特殊人群、国家发展水平、研究设计类型、样本量、检测方法均未见统计学意义。大部分研究表明无症状感染者的病毒载量与有症状患者相似。结论 SARS-CoV-2感染中无症状感染比例一般;18-64岁年龄段较其它年龄段无症状感染比例更高;Omicron病毒株较Delta及其它毒株无症状感染比例更高。

    Abstract:

    Objective In order to objectively and scientifically describe the epidemiological characteristics of asymptomatic infected persons in the Novel Coronavirus infection spectrum. Methods Relevant studies published up to March 2021 were retrieved through systematically searching on PubMed ,CNKI and Wanfang Database. R Version 4.1.3 software was used for Meta analysis of the included studies. Results A total of 53 studies were included, and asymptomatic infection accounted for 28.47% (95%CI: 22.05%, 35.9%) of patients infected with SARS-CoV-2. Meta-subgroup analysis showed that the proportion of asymptomatic SARS-CoV-2 infection among different age groups and strain types was statistically significant. There was no statistical significance in different region (continent), occupation, special population groups, national development level, study design type, sample size and detection method. Most studies show that asymptomatic infected people have viral loads similar to those of symptomatic patients. Conclusion The proportion of asymptomatic infection in SARS-COV-2 infection was general. Asymptomatic infection rates are higher in 18-64 year olds than in other age groups; The Omicron strain has a higher incidence of asymptomatic infection than Delta and other strains.

    参考文献
    相似文献
    引证文献
引用本文
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2022-03-03
  • 最后修改日期:2022-05-28
  • 录用日期:2022-08-11
  • 在线发布日期:
  • 出版日期: