Abstract:Objective In order to objectively and scientifically describe the epidemiological characteristics of asymptomatic infected persons in the Novel Coronavirus infection spectrum. Methods Relevant studies published up to March 2021 were retrieved through systematically searching on PubMed ,CNKI and Wanfang Database. R Version 4.1.3 software was used for Meta analysis of the included studies. Results A total of 53 studies were included, and asymptomatic infection accounted for 28.47% (95%CI: 22.05%, 35.9%) of patients infected with SARS-CoV-2. Meta-subgroup analysis showed that the proportion of asymptomatic SARS-CoV-2 infection among different age groups and strain types was statistically significant. There was no statistical significance in different region (continent), occupation, special population groups, national development level, study design type, sample size and detection method. Most studies show that asymptomatic infected people have viral loads similar to those of symptomatic patients. Conclusion The proportion of asymptomatic infection in SARS-COV-2 infection was general. Asymptomatic infection rates are higher in 18-64 year olds than in other age groups; The Omicron strain has a higher incidence of asymptomatic infection than Delta and other strains.