Objective：To evaluation the role of myocardial perfusion ，viability and MRI cine in myocardial infarction of pig model and patients. Methods：14 pigs with myocardial infarction（3 days），12 pigs with myocardial infarction（3 weeeks） and 17 patients underwent MR scanning. MR cine imaging acquaired by BFFE sequence were used to analyze the motion of heart. T1TFE sequence was used to detect the first pass perfusion after injection of Gd-DTPA（0.1 mmol／kg）. Inversion recovery viability sequence was used to recognize the high signal in the infarct myocardia. Results：The incidence of the low signal detected in the first pass perfusion weighted images in the infarct myocardia of 3-days ｐigs，3-weeks pigs and 17 patients were respectively 100％，92％and 82.3％. The incidence of enhancement region detected in the delayed viability sequence images in the infarct myocardia of 3-days pigs，3-weeks pigs and 17 patients were respectively 7％, 50％and 88.2％. The myocardial wall of hyper enhancement had a weaken motion in MR cine images. The symptom of attenuation and keeping low signal of myocardial wall in viability images was detected in the obvious fibrosis myocardia or scar. Conclusion：The combination of all image findings in the first pass perfusion, viability imaging and cine MR might discriminate the true infarction and scar of heart effectirely.