Objective:To discuss the variety of T-lymphocytes and the combining TB infection of the HIV infected people in Jiangsu province to provide the reference for anti-virus treatment. Methods:The T-lymphocytes subsets from the samples of 140 normal people and 116 HIV infected people were analyzed by flow cytometry. The combining TB infection situation of the HIV infected people were detected by X-ray and sputum examination. Results:The total count of CD4+ T-lymphocytes was lower in HIV infected people than that of normal people(P < 0.001). CD4+/CD8+ ratio of all infected people was obviously lower than that of normal people(P < 0.001). 37.07% infected people had CD4+ T-lymphocytes count lower than 200 -滋l. The CD8+ T-lymphocytes counts and the Th/Ts of the two groups had significant difference. 90 of the 116(77.59%) HIV infected people didn’t have clinical symptoms and the others appeared related clinical symptoms. The CD4+ T-lymphocyte count and the ratio of the Th/Ts between two groups had significant difference. 11 HIV infected people were also infected by TB. Conclusion:When the object was infected by HIV, the number of CD4+ T-lymphocyte count and CD8+ T-lymphocyte count were firmly correlated with the course of disease. Both CD8+ and CD4+ testing was superior to single testing.