文章摘要
吴 波,殷凯生,陆国础,卞 涛,叶万忠.异机融合99Tcm-MIBI SPECT/CT对肺癌诊断的临床价值[J].南京医科大学学报,2008,28(9):1166~1169
异机融合99Tcm-MIBI SPECT/CT对肺癌诊断的临床价值
Clinical evaluation of different-time 99Tcm-MIBI SPECT/CT fusion imaging in diagnosis of patients with lung cancer
投稿时间:2008-01-12  
DOI:10.7655
中文关键词: 肺癌  甲氧基异丁基异腈  图像融合
英文关键词: lung cancer  MIBI  image fusion
基金项目:
作者单位
吴 波 南京医科大学第一附属医院呼吸科,江苏 南京 210029 
殷凯生 南京医科大学第一附属医院呼吸科,江苏 南京 210029 
陆国础 无锡市人民医院呼吸科,江苏 无锡 214023 
卞 涛 无锡市人民医院呼吸科,江苏 无锡 214023 
叶万忠 江苏省原子医学研究所,江苏 无锡 214063 
摘要点击次数: 1893
全文下载次数: 204
中文摘要:
      目的:探讨99Tcm-MIBI SPECT/CT异机融合断层显像对肺癌的临床诊断价值?方法:选择65例肺部占位性病变患者行99Tcm-MIBI SPECT/CT异机融合断层显像,分析显像结果,计算SPECT/CT断层融合显像的摄取比值(UR);依据病理诊断将患者分成肺癌组和良性病变组,以良性病变组UR的x + 1s为诊断阈值,评价其对肺癌的诊断效能?结果:45例肺癌患者SPECT断层融合显像的UR为2.56 ± 0.53;20例肺部良性病灶患者UR为1.47 ± 0.42,差异有统计学意义(P < 0.05);99Tcm-MIBI SPECT/CT异机融合断层显像对肺癌诊断的灵敏度?特异度和准确度分别为86.67%?85.00%?86.15%;假阳性率和假阴性率分别为15.00%和13.33%;阳性预测值和阴性预测值分别为92.86%和73.91%?结论:99Tcm-MIBI SPECT/CT异机融合断层显像对肺癌诊断有较高的临床价值,为制定治疗方案提供重要依据?
英文摘要:
      Objective:To explore the clinical Value of different-time 99Tcm-MIBI SPECT/CT fusion imaging for the diagnosis of the lung cancer. Methods:Sixty five patients with pulmonary abnormal lesions were chosen for performing different-time 99Tcm-MIBI SPECT/CT fusion imaging. They were divided into lung cancer and benign groups according to the pathologic results. Then the results were analyzed. The uptake ratio(UR) was calculated. Finally the diagnostic efficacy of different-time 99Tcm-MIBI SPECT/CT fusion imaging for the lung cancer was evaluated by the threshold of x+1s of the lung benign group. Results:The UR value of 45 cases in lung cancer group was 2.56 ± 0.53 at the time of 60 min SPECT/CT fusion imaging,while 20 cases of benign group was 1.47 ± 0.42. There was a significant UR difference in two groups(P < 0.05). Using the x + 1s of benign group UR value as a threshold,the diagnostic sensitivity,specificity and accuracy of different-time 99Tcm-MIBI SPECT/CT fusion imaging for the lung cancer was 86.67%,85.00% and 86.15% respectively. The false positive and false negative rate were 15.00% and 13.33%. The positive and negative predictive value were 92.86% and 73.91%. Conclusion:Different-time 99Tcm-MIBI SPECT/CT fusion imaging may be used in the diagnosis of lung cancer with great value and it could provide the important clinical information for clinical treatment planning.
查看全文   查看/发表评论  下载PDF阅读器