| 郑玉群,王建明,周〓扬,竺丽梅,许卫国.江苏省涂阳肺结核患者治疗依从性现状调查及影响因素分析[J].南京医科大学学报,2009,29(10):1384~1388 |
| 江苏省涂阳肺结核患者治疗依从性现状调查及影响因素分析 |
| Analysis of risk factors of adherence to anti-tuberculosis treatment among pulmonary tuberculosis patients in Jiangsu province,China |
| 投稿时间：2009-03-27 |
| DOI：10.7655 |
| 中文关键词: 肺结核 治疗 依从性 危险因素 |
| 英文关键词: pulmonary tuberculosis treatment adherence risk factor |
| 基金项目:中国全球基金结核病项目实施性研究(TB07-014) |
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| 中文摘要: |
| 目的:探讨江苏省结核病治疗依从性现状并分析其影响因素,为制订有针对性的干预措施提供科学依据?方法:随机抽取13个样本点,各样本点连续性收集2006年1月1日起登记报告的60例涂阳肺结核患者为研究对象,由经过培训的调查员采用结构式调查表进行问卷调查,并分析依从性现状及不规则治疗的影响因素?结果:670名结核病患者在治疗过程中有82人存在不规则服药现象,不规则治疗比例12.2%?不规则服药的主要原因是药物不良反应(37.8%)?患者的文化程度及服药方式是影响依从性的主要影响因素?结论:依从性是当前结核病控制工作的一个重要课题,应当关注重点人群,采取以规范督导为主的综合干预措施降低不规则治疗的风险,提高治愈率? |
| 英文摘要: |
| Objective:To describe the current status of patients’ adherence to anti-tuberculosis medications and identify risk factors associated with treatment interruption in Jiangsu,and provide evidences to explore intervention measures. Methods:13 counties (districts) were randomly sampled as study sites. On each site,60 sputum smear-positive tuberculosis patients registered since January 1,2006 were selected as study subjects and interviewed by a structured questionnaire. Risk factors associated with non-adherence were analyzed. Results:82 of 670 enrolled pulmonary tuberculosis patients interrupted treatment,accounting for 12.2%. Drug side effect was the most important factor causing patients non-adherence(37.8%). Patients’ education and the way of taking medicine were the main influence factors affecting patients’ adherence. Conclusion:More importance should be attached to treatment adherence under the current DOTS strategy. Synthetic measures taken to focus groups can reduce the risk for interruption and increase cure rate. |
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