文章摘要
郑玉群,王建明,周〓扬,竺丽梅,许卫国.江苏省涂阳肺结核患者治疗依从性现状调查及影响因素分析[J].南京医科大学学报,2009,29(10):1384~1388
江苏省涂阳肺结核患者治疗依从性现状调查及影响因素分析
Analysis of risk factors of adherence to anti-tuberculosis treatment among pulmonary tuberculosis patients in Jiangsu province,China
投稿时间:2009-03-27  
DOI:10.7655
中文关键词: 肺结核  治疗  依从性  危险因素
英文关键词: pulmonary tuberculosis  treatment  adherence  risk factor
基金项目:中国全球基金结核病项目实施性研究(TB07-014)
作者单位
郑玉群 东南大学公共卫生学院,江苏 南京〓210009 
王建明 南京医科大学公共卫生学院,江苏 南京〓210029 
周〓扬 江苏省疾病预防控制中心,江苏 南京〓210009 
竺丽梅 江苏省疾病预防控制中心,江苏 南京〓210009 
许卫国 江苏省疾病预防控制中心,江苏 南京〓210009 
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中文摘要:
      目的:探讨江苏省结核病治疗依从性现状并分析其影响因素,为制订有针对性的干预措施提供科学依据?方法:随机抽取13个样本点,各样本点连续性收集2006年1月1日起登记报告的60例涂阳肺结核患者为研究对象,由经过培训的调查员采用结构式调查表进行问卷调查,并分析依从性现状及不规则治疗的影响因素?结果:670名结核病患者在治疗过程中有82人存在不规则服药现象,不规则治疗比例12.2%?不规则服药的主要原因是药物不良反应(37.8%)?患者的文化程度及服药方式是影响依从性的主要影响因素?结论:依从性是当前结核病控制工作的一个重要课题,应当关注重点人群,采取以规范督导为主的综合干预措施降低不规则治疗的风险,提高治愈率?
英文摘要:
      Objective:To describe the current status of patients’ adherence to anti-tuberculosis medications and identify risk factors associated with treatment interruption in Jiangsu,and provide evidences to explore intervention measures. Methods:13 counties (districts) were randomly sampled as study sites. On each site,60 sputum smear-positive tuberculosis patients registered since January 1,2006 were selected as study subjects and interviewed by a structured questionnaire. Risk factors associated with non-adherence were analyzed. Results:82 of 670 enrolled pulmonary tuberculosis patients interrupted treatment,accounting for 12.2%. Drug side effect was the most important factor causing patients non-adherence(37.8%). Patients’ education and the way of taking medicine were the main influence factors affecting patients’ adherence. Conclusion:More importance should be attached to treatment adherence under the current DOTS strategy. Synthetic measures taken to focus groups can reduce the risk for interruption and increase cure rate.
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