文章摘要
陈建伟,王〓杰,刘〓标,丁其勇,黄庆娟.PET/CT与胸部诊断CT在乳腺癌术后随访中的比较[J].南京医科大学学报,2010,(2):195~198213
PET/CT与胸部诊断CT在乳腺癌术后随访中的比较
Impact of 18F-FDG PET/CT compared with diagnostic CT on following-up breast cancer after surgery
  
DOI:10.7655
中文关键词: 乳腺癌  体层摄影术  发射型计算机  脱氧葡萄糖
英文关键词: breast cancer  tomography  emission-computed  deoxyglucose
基金项目:江苏省教育科学“十一五”规划课题资助项目(D/2009/01/105)
作者单位
陈建伟 南京医科大学第一附属医院PET/CT中心,江苏 南京〓210029 
王〓杰 南京医科大学第一附属医院放射科,江苏 南京〓210029 
刘〓标 南京医科大学第一附属医院PET/CT中心,江苏 南京〓210029 
丁其勇 南京医科大学第一附属医院PET/CT中心,江苏 南京〓210029 
黄庆娟 南京医科大学第一附属医院PET/CT中心,江苏 南京〓210029 
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中文摘要:
      目的:探讨PET/CT与胸部诊断CT在乳腺癌术后随访中的应用价值?方法:70例乳腺癌术后患者,共进行18F-脱氧葡萄糖(FDG)PET/CT检查81人次;同日行胸部诊断CT扫描?以活检或手术后病理或随访结果作为参考标准,比较PET/CT与胸部诊断CT图像?结果:其中31人次PET/CT及对应的胸部诊断CT图像均未见病灶?另外50人次共检出372个病灶?PET/CT的总体灵敏度?特异性?准确性?阳性预测值?阴性预测值分别为88.0%?50.0%?84.9%?95.3%?26.8%;而胸部诊断CT检查分别为60.5%?31.6%?57.5%?88.6%?8.3%?对淋巴结转移,PET/CT的灵敏度(100%)高于胸部诊断CT的灵敏度(52.3%)?对骨骼及胸壁软组织转移,PET/CT的灵敏度(98.1%)也高于胸部诊断CT的灵敏度(25.0%)?但是,PET/CT对肺转移灶检测的灵敏度(58.8%)低于胸部诊断CT(98.9%)?结论:对乳腺癌术后淋巴结?骨骼与软组织转移的检测PET/CT优于胸部CT?但PET/CT一次成像技术并不能取代胸部CT,对于怀疑肺部小结节转移的患者,胸部诊断CT扫描是必要的?有益的?
英文摘要:
      Objective:To compare the imaging characteristics of 18F-fluorodeoxyglucose (FDG) PET/CT with same day diagnostic CT on breast cancer patients after surgery. Method:70 breast cancer patients after surgery were enrolled to take 18F-FDG PET/CT for 81 times. All patients underwent PET/CT for diagnostic purposes followed by diagnostic CT in the region of chest with breath hold. Results:31 PET/CT and 31 diagnostic CT results didn’t show any significant lesion. Another 50 studies displayed 372 lesions. The sensitivity,specificity,accuracy,positive productive value,and negative productive value of PET/CT were 88.0%,50.0%,84.9%,95.3%,26.8%,and those of diagnostic CT were 60.5%,31.6%,57.5%,88.6%,8.3%. As far as lymph node metastases were concerned,the sensitivity for PET/CT was 100%,but for diagnostic CT was 52.3%. As for bone and soft tissue metastases,the sensitivity for PET/CT was 98.1%,compared with 25.0% of diagnostic CT. As for pulmonary nodal metastasis,the sensitivity for PET/CT was 58.8%,but for diagnostic CT was 98.9%. Conclusion:PET/CT accurately detects more malignant lesions than CT does for lymph node and bone and soft tissue metastases. However,the diagnostic CT with breath hold will have an advantage over PET/CT on pulmonary metastases,especial small pulmonary node.
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