文章摘要
彭〓雯,王晓东,段〓宇,冯〓雨,冯尚勇,唐〓伟,茅晓东,刘〓超.南京社区人群甲状腺功能异常的流行病学研究[J].南京医科大学学报,2010,(4):464~466521
南京社区人群甲状腺功能异常的流行病学研究
Epidemiologic study of thyroid dysfunction in community population of Nanjing
投稿时间:2009-11-19  
DOI:10.7655
中文关键词: 甲状腺功能异常  亚临床  流行病学研究
英文关键词: thyroid dysfunction  subclinical  epidemiologic study
基金项目:江苏省医学重点人才资助(RC2002043);江苏省科委社会发展基金(BS2004039)
作者单位
彭〓雯 南京医科大学第一附属医院内分泌科,江苏 南京〓210029 
王晓东  
段〓宇  
冯〓雨  
冯尚勇  
唐〓伟  
茅晓东  
刘〓超  
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中文摘要:
      目的:研究南京社区人群甲状腺功能异常的流行病学特点?方法:采用分层整群随机抽样的方法,抽取20岁以上的常住(≥5年)居民1 266人,分别进行问卷调查?体格检查和血清甲状腺功能的测定?结果:①南京地区临床甲状腺功能亢进(甲亢)?亚临床甲亢?临床甲状腺功能减退(甲减)和亚临床甲减的患病率分别为0.55%,1.74%,0.32%和4.82%;②女性人群中,临床甲亢?亚临床甲亢?临床甲减和亚临床甲减的患病率均高于男性人群,但差异未达到统计学意义;③随着年龄增长,甲状腺功能减退的患病率显著增高(ρ=0.097 1,P= 0.000 5)?结论:甲状腺功能异常,尤其是亚临床甲状腺功能异常的患病率较高,需注意筛查?评估和干预?
英文摘要:
      Objective:To investigate the prevalence of thyroid dysfunction in Nanjing community population. Methods:The residents who had lived in Nanjing for at least five years and were more than 20 years old were selected by a stratified cluster sampling technique. 1 266 subjects were selected for questionnaire,physical examination and serum thyroid function test. Results:① Prevalences of overt hyperthyroidism,subclinical hyperthyroidism,overt hypothyroidism and subclinical hypothyroidism were 0.55%,1.74%,0.32% and 4.82% respectively in Nanjing city. ②The prevalences of overt hyperthyroidism,subclinical hyperthyroidism,overt hypothyroidism and subclinical hypothyroidism in females there all higher than those in male,however,the difference was not significant. ③ The prevalence of hypothyroidism increased significantly with age(ρ=0.0971,P=0.0005). Conclusion:Thyroid dysfunction,especially subclinical thyroid dysfunction is common in Nanjing. Screening,evaluation and intervention for thyroid dysfunction is necessary.
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