文章摘要
成〓浩,徐金水,吴建茹,傅更锋,还锡萍,王〓蓓.江苏省男性HIV感染者/艾滋病人中解脲脲原体和生殖支原体的检测分析[J].南京医科大学学报,2010,(8):1163~1165
江苏省男性HIV感染者/艾滋病人中解脲脲原体和生殖支原体的检测分析
Detection of Ureaplasma urealyticum and Mycoplasma genitalium in male HIV/AIDS population in Jiangsu Province
投稿时间:2010-01-13  
DOI:10.7655
中文关键词: HIV感染者  艾滋病  解脲脲原体  生殖支原体
英文关键词: HIV infector  AIDS patient  Ureaplasma urealyticum  Mycoplasma genitalium
基金项目:国家自然科学基金项目(30872156)
作者单位
成〓浩 东南大学公共卫生学院,江苏 南京〓210009 
徐金水 江苏省疾病预防控制中心性病艾滋病防治所,江苏 南京〓210024 
吴建茹 东南大学公共卫生学院,江苏 南京〓210009 
傅更锋 江苏省疾病预防控制中心性病艾滋病防治所,江苏 南京〓210024 
还锡萍 江苏省疾病预防控制中心性病艾滋病防治所,江苏 南京〓210024 
王〓蓓 东南大学公共卫生学院,江苏 南京〓210009 
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中文摘要:
      目的:调查江苏省男性HIV感染者/艾滋病人解脲脲原体(Ureaplasma urealyticum,Uu)和生殖支原体(Mycoplasma genitalium,Mg)的感染情况,为进一步的研究和分析其与艾滋病进程之间的关系提供基本信息?方法:采集调查对象的首段尿液,Uu检测采用培养鉴定法,Mg检测采用巢式PCR技术?结果:江苏省男性HIV+/AIDS患者中Uu和Mg的检出率分别为51.71%和28.97%;不同地区患者的支原体感染情况存在差异;HIV+/AIDS患者外周血CD4+细胞计数越低,Mg感染率越高,二者之间的负关联具有统计学意义?结论:江苏省男性HIV+/AIDS患者中存在较高的Uu和Mg的感染状况;Mg感染与机体的免疫状况可能相关?
英文摘要:
      Objective:To examine the prevalence of Ureaplasma urealyticum and Mycoplasma genitalium in male HIV/AIDS patients in Jiangsu Province,in order to provide evidence for future researches on the role of these two mycoplasmas in AIDS. Methods:The organisms were detected from first-void urine specimens in males. Ureaplasma urealyticum was detected by culture method,whereas nested-PCR was used to detect Mycoplasma genitalium. Results:The prevalences of Ureaplasma urealyticum and Mycoplasma genitalium in male HIV/AIDS patients in Jiangsu Province were 51.71% and 28.97%,respectively;the rates of different areas were various. The association of Mycoplasma genitalium infection with the CD4+ cell counts in HIV/AIDS patients was significant. Conclusion:The prevalences of Ureaplasma urealyticum and Mycoplasma genitalium in male HIV/AIDS patients in Jiangsu Province were both high,and Mycoplasma genitalium infection may connect with people’s immune status.
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