文章摘要
杨丹丹,邵 燕,虞 浩,王建明,许卫国,陆 伟,羊海涛.江苏省耐药结核病抽样调查研究[J].南京医科大学学报,2011,(7):1007~1010
江苏省耐药结核病抽样调查研究
Epidemiology of anti-tuberculosis drug resistance in Jiangsu province
投稿时间:2011-01-28  
DOI:10.7655
中文关键词: 肺结核  江苏省  耐药
英文关键词: tuberculosis  Jiangsu province  drug resistance
基金项目:国家科技重大专项课题(2009ZX10004-904)
作者单位
杨丹丹 江苏省疾病预防控制中心慢传科,江苏 南京 210009 
邵 燕 江苏省疾病预防控制中心慢传科,江苏 南京 210009 
虞 浩 江苏省疾病预防控制中心慢传科,江苏 南京 210009 
王建明 南京医科大学公共卫生学院流行病与卫生统计学系,江苏 南京 210029 
许卫国 江苏省疾病预防控制中心慢传科,江苏 南京 210009 
陆 伟 江苏省疾病预防控制中心慢传科,江苏 南京 210009 
羊海涛 江苏省疾病预防控制中心慢传科,江苏 南京 210009 
摘要点击次数: 1291
全文下载次数: 118
中文摘要:
      目的:了解江苏省耐药结核病流行状况,为江苏省结核病防治规划修订和完善提供科学依据?方法:按WHO/IUATLD《结核病耐药监测指南》要求进行抽样和药物敏感性检测?结果:①江苏省肺结核患者总耐药率为40.96%,初始耐药率为32.80%,获得性耐药率为55.90%;总耐多药率16.61%,初始耐多药率7.63%,获得性耐多药率33.07%;②不同年龄组?不同学历?不同地区和是否有中断史的肺结核患者的耐药分布有差异?结论:江苏省肺结核患者的耐药情况不容乐观,需要引起重视?耐药主要发生在经济欠发达地区,以中年和文化程度低者为主,有中断治疗史患者发生耐药危险较高?
英文摘要:
      Objective:To evaluate the prevalence of anti-tuberculosis drug resistance (DR) among tuberculosis (TB) patients in Jiangsu province and provide statistical data for government to prevent and control TB. Methods:The TB patients in Jiangsu province were sampled and drug susceptibility test(DST) was carried out according to the “Guidelines for surveillance of drug resistance in tuberculosis” developed by WHO/IUATLD. Results:①The DST results showed that 40.96% Mycobacteria tuberculosis strains were resistant to at least one drug we tested, and the proportion was 32.80% among new cases and 55.90% among previously treated ones. The prevalence of multidrug-resistant(MDR) TB was 16.61%, with a significant difference in new cases (7.63%) and in previously treated cases(33.07%). ② Patients in middle-age or with lower education background or living in the middle or north part of Jiangsu province had higher risks for DR or MDR. Conclusion:The high prevalence of drug resistance in Jiangsu province has been a major challenge for TB control.
查看全文   查看/发表评论  下载PDF阅读器