Objective: To investigate the epidemiologic characteristics of the deleted cases of syphilis and gonorrhea in Jiangsu province from 2006 to 2010, and to provide scientific references for the further report and control of these diseases. Methods: The deleted cases of syphilis and gonorrhea reported in China Information System for Disease Control and Prevention in Jiangsu province were collected and the data were analyzed. Results: The proportions of deleted cases of syphilis and gonorrhea in total reported syphilis and gonorrhea cases were increased;the experimental diagnostic cases were increased,while clinical diagnostic cases were decreased in deleted cases of syphilis and gonorrhea. Most deleted cases aged from 15 to 49 years old,and most cases were deleted by integrative hospitals;the majority of deleted cases were reported in the south of Jiangsu province. Conclusion: The deleted cases of syphilis and gonorrhea are increased in Jiangsu province,a series of strategies should be strengthened on cases report and prevention in sexually transmitted diseases (STDs) in order to improve the timely,integrated and accurate cases report of STDs.