Objective:To study the relationship between hyperuricemia and disease related to metabolic in the elderly. Methods:All 7304 adults above 60 years were enrolled in 2009~2010 at the medical examination center of the First Affiliated Hospital of NJMU. The medical history,the biochemical index and the general physical data were evaluated. The sex-specific cutoff for serum uric acid quartiles and multiple stepwise by multinomial Logistic regression model was used to analyze the relationship between uricemia and ages,sex,cholesterol,and other factors related to metabolism. Results:The incidence rates of hyperuricemia in men were higher than that in women at the same age group. The uric acid level increased with the ages. BMI,systolic blood pressure and diastolic blood pressure,fasting plasma glucose,especially TG and TG/HDL-C were positively correlated with blood uric acid(P < 0.05). The blood uric acid level was also positively correlated with blood pressure grades. Blood uric acid level of those with IFG was significantly higher than that of diabetic patients. The incidence of diabetes mellitus increased in hyperuricemia group than the non- hyperuricemia group. The blood uric acid level was positively associated with blood glucose in men,no such correlation observed in women. When the sex-specific cutoff for serum uric acid quartiles and multinomial Logistic regression model were used,the analysis revealed that ages,BMI,blood pressure,cholesterol,high density lipoprotein,cholesterol,TG/HDL-C,fasting plasma glucose and blood uric acid levels were significantly positive correlated. Conclusion:The blood uric acid level was closely related to ages,BMI,hyperlipidemia,hyperglycemia,hypertension and other constitution of metabolism. It is important to investigate the possible benefits of anti-hyperuricemia treatment for preventing complications in cardio-celebral-vascular system.