文章摘要
汪 涛,高 飞,陈 嘉,王 钢,沈历宗.单中心食管胃结合部腺癌发病情况11年变化趋势[J].南京医科大学学报,2014,(9):1232~1235
单中心食管胃结合部腺癌发病情况11年变化趋势
Prevalence trend of adenocarcinoma of esophagogastric junction in a single institution in China
投稿时间:2013-12-02  
DOI:10.7655/NYDXBNS20140916
中文关键词: 食管胃结合部腺癌  胃癌  发病趋势
英文关键词: adenocarcinoma of esophagogastric junction  gastric cancer  prevalence
基金项目:国家自然科学基金面上项目(81272711)
作者单位
汪 涛 南京医科大学第一附属医院普通外科,江苏 南京 210029 
高 飞 南京医科大学第一附属医院普通外科,江苏 南京 210030 
陈 嘉 南京医科大学第一附属医院普通外科,江苏 南京 210031 
王 钢 南京医科大学第一附属医院普通外科,江苏 南京 210032 
沈历宗 南京医科大学第一附属医院普通外科,江苏 南京 210033 
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中文摘要:
      目的:研究食管胃结合部腺癌(adenocarcinoma of the esophagogastric junction,AEG)发病情况的变化趋势?方法:回顾分析2001年1月~2011年12月南京医科大学第一附属医院收治的4 685例胃癌病例,其中AEG1 824例,非食管胃结合部腺癌(non-esophagogastric junction adenocarcinoma,NEGA)2 861例?研究AEG在胃癌中所占比例变化趋势?早期食管胃结合部腺癌(early adenocarcinoma of esophagogastric junction,EAEG)检出率变化趋势?AEG 性别年龄分布及比较AEG和NEGA患者发病年龄和性别比的差异?结果:该中心11年来AEG在胃癌中所占比例无明显变化;2007~2011年EAEG的检出率为12.23%(135/1 104),2001~2006年为8.47%(61/720),前者显著高于后者(P = 0.013);AEG患者平均发病年龄以及男女性别比均显著高于NEGA患者[(62.7 ± 9.5)岁 vs (59.1 ± 12.7)岁,P < 0.001;1 434∶390 vs 1 990∶871,P < 0.001)]?结论:AEG在胃癌中所占比例无明显增高;近5年EAEG检出率显著增高;AEG好发于男性老年患者?
英文摘要:
      Objective:To investigate the veriation trend of the prevalence of adenocarcinoma of esophagogastric junction (AEG). Methods:The medical records of 4 685 cases diagnosed with gastric cancer in the First Affiliated Hospital of NJMU between 2001 and 2011 were reviewed and analyzed retrospectively. There were 1 824 cases of AEG and 2 861 non-esophagogastric junction adenocarcinoma (NEGA) among them. The veriation trend of proportion of AEG and early adenocarcinoma of esophagogastric junction (EAEG) as well as the distribution of age and gender were evaluated and the average age and the ratio of male to female were compared between the AEG and NEGA group. Results:The proportion of AEG in gastric cancer had not changed during the past 11 years,however,the proportion of EAEG was significantly higher between 2007 and 2011 than that in the period from 2001 to 2006 (12.23% vs 8.47%,P = 0.013). Compared with the NEGA group,patients in the AEG group had higher mean age [(62.7 ± 9.5)vs (59.1 ± 12.7)years,P < 0.001)]and male to female ratio (1 434∶390 vs 1 990∶871,P < 0.001). Conclusion:The prevalence of AEG in gastric cancer was not significantly increased,whereas the proportion of EAEG over the past 5 years was significantly increased. AEG occurs more often in elderly male patients.
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