文章摘要
马 丹,孙敏讷,丁国宪,盛云露,段 宇.老龄人群甲状腺功能与身体成分的相关性分析[J].南京医科大学学报,2017,(5):601~606
老龄人群甲状腺功能与身体成分的相关性分析
Correlation between thyroid function and body composition in the elderly with euthyroid gland
投稿时间:2017-02-03  
DOI:10.7655/NYDXBNS20170517
中文关键词: 正常甲状腺功能  甲状腺激素  老龄人群  身体成分
英文关键词: euthyroidism  thyroid hormone  the elderly  body composition
基金项目:国家自然科学基金(81670724,91649122)
作者单位
马 丹 南京医科大学第一附属医院内分泌科 
孙敏讷 老年内分泌科江苏 南京 210029 
丁国宪 老年内分泌科江苏 南京 210029 
盛云露 老年内分泌科江苏 南京 210029 
段 宇 南京医科大学第一附属医院内分泌科 
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中文摘要:
      目的:探索老龄人群中甲状腺激素与肌肉及脂肪等身体成分的内在联系。方法:74例年龄≥60岁的甲状腺功能正常的健康体检者,平均年龄(74.6±7.7)岁,测定其体重、甲状腺功能及身体成分等。结果:游离三碘甲状腺原氨酸(free triiodothyronine,FT3)与四肢肌肉质量(appendicular muscle mass , ASM)呈正相关(P=0.003),校正年龄、性别及体重指数(body mass index,BMI)后二者间仍存在正相关性(P=0.011);FT3与总肌肉量(去除头部)呈正相关(P=0.024),校正年龄、性别及BMI后仅发现女性入组者中二者仍呈正相关,而男性中未见明显相关;促甲状腺激素(thyroid stimulating hormone, TSH)与四肢脂肪含量、总脂肪量(去除头部)呈负相关(P=0.039;P=0.038),校正混杂因素后并未发现明显相关性。结论:甲状腺功能正常的老龄人群中甲状腺激素水平影响身体成分。
英文摘要:
      Objective: This study is aimed to explore the relationship between thyroid hormone and body composition in the elderly with euthyroid gland. Methods: Seventy-four euthyroid subjects with an average age 74.6±7.7 years old have been involved. Body weight, thyroid function and body composition have been measured. Results: Appendicular muscle mass (ASM) was positively associated with FT3(P=0.003). There is still a positive correlation between the two indexes after adjusting for age, sex and body mass index(BMI) (P=0.011). FT3 was positively correlated with lean subtotal(P=0.024). We found the same correlation between ASW and FT3 in female(P=0.043), but not male, after adjusting for age, sex and BMI.TSH was negatively correlated with appendicular fat mass and fat subtotal(P=0.039; P=0.038).None correlation between the two has been found after adjusting for confounding factors. Conclusion:Thyroid hormone is related with body composition in the elderly with euthyroid gland.
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