Objective：To evaluate the short and medium-clinical effect of acupuncture therapy in treating hot flashes in patients with breast cancer by meta-analysis. Methods: This systematic research analyzed all randomized controlled trials （RCTs） relating with the effects of acupuncture treatment for hot flashes of breast cancer patients in the CNKI，CBM，VIP，Wanfang and PubMed （30th June 2017 ago）. The quality of RCTs was assessed by Cochrane systematic review. Multiple overall effects of results were analyzed with meta-analysis，and evaluated systematically by RevMan5.3 software. The heterogeneity was evaluated. Results: In the follow-up visit of 3 months （SMD=-0.36，95%CI: -0.61~-0.10） and 6 months （SMD=-0.41，95%CI: -0.64~-0.18），acupuncture improved the syndrome systematically （P=0.006，P=0.000 5，respectively）. Conclusion: The results of clinical researches with high study quality show that acupuncture treatment can significantly improve the syndrome of hot flashes in short- and medium-term in breast cancer patient.