文章摘要
蔡明璇,徐 艳,李 璐.应用不同骨材料进行拔牙位点保存的效果评价[J].南京医科大学学报,2019,(2):278~283
应用不同骨材料进行拔牙位点保存的效果评价
Effects of ridge preservation following tooth extraction with different bone graft materials
投稿时间:2018-01-31  
DOI:10.7655/NYDXBNS20190227
中文关键词: 位点保存  骨材料  临床疗效  锥形束CT
英文关键词: ridge preservation  bone materials  clinical effects  CBCT
基金项目:国家自然科学基金(81771074,81470749);江苏省高校自然科学研究重大项目(16KJA320001);江苏省高层次卫生人才“六个一”工程(LGY2016048);江苏省高校优势学科建设工程资助(2014?37);江苏省自然科学基金(BK20171058);江苏省高等学校大学生创新创业训练计划(201710312014Z)
作者单位
蔡明璇 南京医科大学附属口腔医院牙周科南京医科大学江苏省口腔疾病研究重点实验室江苏 南京 210029 
徐 艳 南京医科大学附属口腔医院牙周科南京医科大学江苏省口腔疾病研究重点实验室江苏 南京 210029 
李 璐 南京医科大学附属口腔医院牙周科南京医科大学江苏省口腔疾病研究重点实验室江苏 南京 210029 
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中文摘要:
      目的:评价重度牙周炎非磨牙患牙进行拔牙位点保存的效果,比较分析Bio?Oss和Bio?Gene骨材料单独及联合应用于拔牙位点保存的疗效。方法:选取南京医科大学附属口腔医院牙周科患者26例,共计重度牙周炎非磨牙患牙32颗,随机分为4组,于牙周翻瓣术中拔除,实验组患牙同期分别植入Bio?Oss、Bio?Gene以及等比混合的Bio?Oss及Bio?Gene材料,对照组自然愈合。术前、术后即刻和术后6个月分别进行临床观察,并拍摄锥形束CT(cone beam CT,CBCT)测量相应骨高度、宽度及密度变化值,数据分析采用单因素方差分析及LSD?t检验。结果:临床观察显示,拔牙后6个月,对照组的牙槽骨吸收明显,牙槽嵴窄平,而实验组骨吸收较少,牙槽嵴保存丰满。CBCT检查显示,术前与术后6个月骨高度和宽度变化比较,对照组与3个实验组组间差异有统计学意义(P<0.05);术后即刻与术后6个月骨高度、宽度和密度变化比较,实验组中混合组变化最小,Bio?Oss组其次,Bio?Gene组最大,组间差异有统计学意义(P<0.05)。结论:对于重度牙周炎非磨牙患牙,拔牙同期位点保存比自然愈合在牙槽骨量的维持上具有优势;等比混合Bio?Oss及Bio?Gene材料对牙槽骨量的维持优于单独应用一种材料。
英文摘要:
      Objective:To evaluate the effects of ridge preservation in non?molar sites with advanced periodontitis,and to compare the effects of Bio?Oss,Bio?Gene and equal?ratio mixed of both materials. Methods:A total of 26 patients with 32 non?molar regions who were diagnosed with advanced periodontitis at our institution were included. They were classified into three experimental groups and one control group. The experimental groups were grafted with Bio?Oss,or Bio?Gene or the equal?ratio mixed of both materials after the tooth extraction,while the control group did not graft any meterials. Clinical and CBCT parameters were measured before,immediately and 6 months after the extraction. Data statistics used one?way ANOVA and LSD?t analysis. Results:The alveolar ridges of the control group were narrow,while the experimental groups were relatively plump at 6 months after the extraction. The difference of changes of alveolar bone height and width among the control and experimental groups was statistically significant(P<0.05). The changes of alveolar bone height,width and density postoperatively of the mixed group were minimal,then was the Bio?Oss group,and last was the Bio?Gene group. The difference among the experimental groups was statistically. Conclusion:Ridge preservation after the extraction was superior in the maintenance of soft and hard tissues. The equal?ratio mixed of Bio?Oss and Bio?Gene was better than either one alone.
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