文章摘要
段丽珍,郭莉莉.磁共振肿瘤靶向分子探针的研究进展[J].南京医科大学学报,2019,(11):1681~1685
磁共振肿瘤靶向分子探针的研究进展
Progresses in magnetic resonance tumor⁃targeting molecular probes
投稿时间:2019-02-02  
DOI:10.7655/NYDXBNS20191132
中文关键词: 磁共振成像  肿瘤  分子成像  分子探针
英文关键词: magnetic resonance imaging  tumor  molecular imaging  molecular probe
基金项目:南京医科大学科技发展基金基金(2016NJMUZ D085)
作者单位
段丽珍 南京医科大学附属淮安第一医院影像科江苏 淮安 223300 
郭莉莉 南京医科大学附属淮安第一医院影像科江苏 淮安 223300 
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中文摘要:
      磁共振分子成像是早期特异性诊断肿瘤的一种重要手段,凭借其无创、无电离辐射和较高的软组织分辨力等优势获得了广阔的发展前景。磁共振肿瘤靶向分子探针的设计与开发是肿瘤分子显像的关键,运用不同的分子识别系统研发多种特异性靶向亲和探针,以达到对肿瘤的基因及特征性分子进行成像的目的。文章就近年来磁共振肿瘤分子探针的最新进展展开综述。
英文摘要:
      Magnetic resonance molecular imaging is an important method for early diagnosis of tumors. It has broad prospects for its advantages of non?invasive,non?ionizing radiation and high soft tissue resolution. The design and development of magnetic resonance tumor?targeted molecular probes are keys to tumor molecular imaging. Different molecular recognition systems are used to develop a variety of specific targeted affinity probes,and to achieve the purpose of tumor genes and characteristic molecules imaging. In this paper,the latest progresses of magnetic resonance tumor molecular probes in recent years are reviewed.
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