CAT评分联合指脉氧监测在慢性阻塞性肺病管理中的应用价值
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The application value of COPD assessment test(CAT)and monitoring oxygen saturation in management of patients with chronic obstructive pulmonary disease
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    摘要:

    目的:探讨慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)评估测试(COPD assessment test,CAT)联合指脉氧监测在COPD患者管理中的应用价值。方法:分析57例COPD患者CAT评分、日常步行运动指脉氧、COPD指脉氧评估测试(COPD assessment test and SpO2,CATS)与肺功能之间的相关性,比较少症状组(CAT<10分)、多症状组(CAT≥10分)患者指脉氧的差异。结果:CAT总分、症状相关评分、生活状态评分均与第1秒用力呼气的容积占预计值的百分比(FEV1%pred)呈负相关;静息指脉氧(SpO2B)、最低指脉氧(SpO2L)与FEV1%pred呈正相关,ΔSpO2与FEV1%pred呈负相关;CATS与FEV1%pred呈负相关,与生活状态评分呈正相关。其中,少症状组生活状态评分及SpO2B与FEV1%pred有相关性;多症状组CAT总分、生活状态评分、ΔSpO2与FEV1%pred呈负相关,SpO2L与FEV1%pred呈正相关。多症状组的SpO2B与SpO2L均低于少症状组,而ΔSpO2高于少症状组。结论:指脉氧监测有助于发现COPD急性加重期患者;CAT评分中的生活状态评分较症状相关评分与COPD患者肺功能关系更为密切;指脉氧监测与CAT评分联合即CATS有助于COPD的管理和精准治疗。

    Abstract:

    Objective:To investigate the application value of chronic obstructive pulmonary disease(COPD)assessment test(CAT)and monitoring pulse oxygen saturation(SpO2)in management of patients with COPD. Methods:The correlations of CAT,SpO2 during walking,CAT and SpO2(CATS)with pulmonary function were analyzed respectively. The difference of SpO2 was also analyzed between the two groups which were defined as CAT<10 and CAT≥10. Results:CAT total score,respiratory CAT score,non-respiratory CAT score,SpO2B,SpO2L,ΔSpO2,CATS were all associated with FEV1(forced expiratory volume in 1 second)% predicted. CATS was also associated with non-respiratory CAT score. In CAT<10 group,non-respiratory CAT score and SpO2B were associated with FEV1%pred. In CAT ≥10 group,CAT total score,non-respiratory CAT score,SpO2L and ΔSpO2 were associated with FEV1%pred. The SpO2B and SpO2L in CAT≥10 group were higher,and ΔSpO2 was lower than those in CAT<10 group. Conclusion:Monitoring oxygen saturation may be helpful in diagnosis of acute exacerbation of COPD patients. Non-respiratory CAT score contributes more to CAT total score than respiratory CAT score. CATS,the combination of oxygen saturation and CAT,will improve the management of COPD and precision medicine treatment.

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李媛媛,陈良玉,孙培莉. CAT评分联合指脉氧监测在慢性阻塞性肺病管理中的应用价值[J].南京医科大学学报(自然科学版),2020,(1):77-81

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  • 收稿日期:2019-06-25
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  • 在线发布日期: 2020-02-09
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