As the largest microecosystem in human body，intestinal microecology is considered as an organ regulating host metabolism. A large number of microorganisms in the human intestinal tract are known as the gut microbiota，their changes in species composition，quantitative imbalance，the colonization and translocation，as well as their metabolites are closely related to the development of hyperuricemia and gout. This review focuses on the correlation between hyperuricemia，gout and gut microbiota，and further explores the correlation including the mechanism，diagnosis，treatment and other aspects，this will provide new ideas for the clinical diagnosis and treatment of hyperuricemia and gout.