不同年龄段高龄孕妇妊娠风险的相关性分析
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国家重点研发计划(2016YFC1000300);国家自然科学基金(81571458、81100436);江苏省六大高峰高层次人才培养项目(WSW?121)


Correlation analysis of pregnancy outcome risk in pregnant women with different advanced maternal ages
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    摘要:

    目的:通过比较不同年龄段高龄孕妇妊娠结局的差异,探讨年龄与不良妊娠结局的相关性,有助于指导高龄孕妇的孕期管理。方法:回顾性收集2019年1—7月在南京医科大学附属妇产医院产科分娩的1 342例高龄孕妇的临床资料,应用四分位数法对年龄进行分组,其中35~<36岁组355例,36~<37岁341例,37~<39岁组366例,≥39岁组280例,以35~<36岁为参考组,比较和分析其他3组与参考组间不良妊娠结局发生率的差异。结果:各组之间孕妇孕次、产次、受孕方式、新生儿不良结局无显著差异(P > 0.05),而妊娠合并糖尿病、前置胎盘及剖宫产率随着年龄的增加有升高趋势(P < 0.05)。结论:高龄产妇随着年龄增加,多种不良妊娠结局的发生率总体呈升高趋势,以39岁后更为显著。

    Abstract:

    Objective:This study aims to compare the adverse pregnancy outcomes of advanced maternal age women in different age groups and explore the association between age and adverse pregnancy outcomes. Methods:A total of 1 342 women of advanced maternal age from January 2019 to July 2019 in Women’s Hospital of Nanjing Medical University were enrolled in this study. All the women were divided into four groups according to different age using quartiles,the 35~<36 years group,36~<37 years group,37~<39 years group and ≥39 years group. The 35~<36 years group was taken as the reference group. Comparisons of adverse pregnancy outcomes incidence between another three groups and the reference group were performed. Results:The comparsions of gravidity,parity and conception ways showed no significances among four groups. The incidence of gestational diabetes,placenta previa and cesarean delivery increased with age(P < 0.05). Conclusion:The incidence of multiple adverse pregnancy outcomes generally increased with age,which is more significant in wowen with ≥39 years old

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林 宇,石中华.不同年龄段高龄孕妇妊娠风险的相关性分析[J].南京医科大学学报(自然科学版),2020,(12):1824-1828

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  • 收稿日期:2020-05-19
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  • 在线发布日期: 2021-01-04
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