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Study on CO2-supercritical fluid extraction used to extract three kinds of tanshinones from the root of salvia meltiorrhiza bunge with different entrainers
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    Objective: To extract three kinds of tanshinones from the root of Salvia miltiorrhiza Bunge by CO2-supercritical fluid extraction technology with different entrainers at different flow rates, and to investigate the effects of different entrainers. Methods:Three kinds of tanshinones were extracted at the optimal operation condition, and the massconcentration of three kinds of tanshinones in the extracts was determined by HPLC. Results: Among the three entrainers, the extracting effects of ethanol is the best, for the stronger polarity, followed by ethanol and normal octane. Conclusion: To increase the extracting rate of three kinds of tanshinones by CO2-supercritical fluid extraction technics, it is essential to use polar solvent as entrainer.

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Guozhang Li, Huazhong Yu, Xiaoying Bu, Yong Cao, Liqun Rao.[J].南京医科大学学报(自然科学版),2006,20(2):

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