文章摘要
Jiageng Zhu, Jun Li, Ruipeng Jia,Jianghao Su, Mingshun Shen,Zhigang Cao.[J].南京医科大学学报,2007,(2):125~128
Research of combined liver-kidney transplantation model in rats
投稿时间:2006-10-18  
DOI:10.7655
中文关键词: 
英文关键词: liver  kidney  transplantation  rat
基金项目:
作者单位
Jiageng Zhu Department of Urology Nanjing First Hospital of Nanjng Medical University Nanjing 210006 China 
Jun Li  
Ruipeng Jia  
Jianghao Su  
Mingshun Shen  
Zhigang Cao  
摘要点击次数: 960
全文下载次数: 1015
中文摘要:
      
英文摘要:
      Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer’s was infused from porta1 veins to donated 1ivers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.
查看全文   查看/发表评论  下载PDF阅读器