文章摘要
Xingli Zhang,Jinchang Wu.[J].南京医科大学学报,2009,29(1):1~5
Establishing of the Transplanted Animal Models for Human Lung Cancer
投稿时间:2008-10-07  
DOI:10.7655
中文关键词: 
英文关键词: lung cancer  transplanted animal models  establish animal models
基金项目:
作者单位
Xingli Zhang Department of Radiotherapy of Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou 215001, China 
Jinchang Wu  
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中文摘要:
      
英文摘要:
      Lung cancer is the leading cause of cancer mortality worldwide.Even with the applications of excision, radiotherapy, chemotherapy, and gene therapy, the 5 year survival rate is only 15% in the USA. Clinically relevant laboratory animal models of the disease could greatly facilitate understanding of the pathogenesis of lung cancer, its progression, invasion and metastasis. Transplanted lung cancer models are of special interest and are widely used today. Such models are essential tools in accelerating development of new therapies for lung cancer. In this communication we will present a brief overview of the hosts, sites and pathways used to establish transplanted animal lung tumor models.
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