文章摘要
Rui Wu,Xilong Zhang,Ling Hu,Enzhi Jia.[J].南京医科大学学报,2009,29(1):59~63
Relationship between obstructive sleep apnea hypopnea syndrome and cardiovascular disorders in adult snorers
投稿时间:2008-09-23  
DOI:10.7655
中文关键词: 
英文关键词: Obstructive sleep apnea hypopnea syndrome  cardiovascular disorder  snoring
基金项目:
作者单位
Rui Wu Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China 
Xilong Zhang Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China 
Ling Hu Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China 
Enzhi Jia Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China 
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中文摘要:
      
英文摘要:
      Objective:To investigate the relationship between sleep apnea hypopnea syndrome (OSAHS) and some cardiovascular disorders in adult habitual snorers as well as the effectiveness of nasal continuous positive airway pressure on those with OSAHS. Methods:With the use of polysomnography, 262 adult habitual snorers were examined and divided into the OSAHS group and the Non-OSAHS group (control). Using ambulatory electrocardiogram and blood pressure measurement, daily nocturnal rhythm of blood pressure, hypertension, heart rate variability, some arrythmias and angina pectoris of coronary heart disease were monitored and compared between the two groups, before and after 14 days of treatment with nasal continuous positive airway pressure in the OSAHS group. Results:This study indicated a higher incidence (39.6%) of OSAHS in adult snorers and demonstrated that there was a significantly higher incidence of hypertension, disappearance of the daily nocturnal rhythm of blood pressure, poor effectiveness of nitrate on angina pectoris of coronary heart disease, decreased heart rate variability during sleep, increased arrythmias and lower SpO2 levels in the OSAHS group than in the Non-OSAHS group. After nasal continuous positive airway pressure treatment during sleep, snoring control, significantly higher SpO2 and lower apnea hypopnea indices were achieved in the OSAHS group; heart rate variability and daily nocturnal rhythm of blood pressure returned to normal levels.Conclusion:The results of this research suggested that there was a close relationship between the development of OSAHS and some cardiovascular disorders. Furthermore, nasal continuous positive airway pressure treatment was effective not only on OSAHS but also on coexisting cardiovascular disorders.
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