Objective：To investigate the maternal and infant outcomes and clinical characteristics of uterine rupture. Methods：The clinical characteristics and maternal and infant outcomes of 70 patients with uterine rupture who delivered in Nanjing Medical University Obstetrics and Gynecology Hospital from 2009 to 2020 were retrospectively analyzed according to whether there was scar uterus or not and the time point when uterine rupture was found. Results：① The incidence of uterine rupture in this study was 0.054%. ② Clinical manifestations：23 cases(32.86%)had abdominal pain，13 cases(18.57%)had vaginal bleeding，9 cases(12.86%) had fetal heart abnormalities，7 cases(10%)had hemodynamic instability，11 cases(15.71%)had bloody amniotic fluid，pathological contraction of loops and other manifestations，and 29 cases(41.43%)had no clinical manifestations. ③ Maternal and infant outcomes： There were 24 cases(34.29%)with complete uterine rupture，4 cases(5.71%)with hysterectomy，30 cases(42.86%)with serious postpartum hemorrhage，21 cases(30%)with massive blood transfusion，and no maternal death. Among the 62 newborns，3 cases (4.84%)died intrauterine，1 case(1.61%)was given up rescue by family members，5 cases(8.06%)had severe neonatal asphyxia，7 cases(11.29%)had mild neonatal asphyxia. ④ Compared with scar uterine rupture，non ⁃ scar uterine rupture was more thanpostpartum rupture(66.67% vs. 16.36%，P ＜ 0.05). Postpartum bleeding rate(80.00% vs. 32.73%)，massive transfusion rate(66.67% vs. 20.00%)and hospitalization cost(26 348.68 yuan vs. 13 859.53 yuan)were significantly increased(P ＜ 0.05)，but there was no significant difference in neonatal outcomes between the two groups(P ＞ 0.05). ⑤ In scarred uterus，the rate of complete uterine rupture (55%)，postpartum hemorrhage(60%)and massive transfusion(45%)in TOLAC group were significantly higher than those in ERCS group(20.00%，17.14%，5.71%，P ＜ 0.05). ⑥ There was no significant difference in maternal and infant outcomes of patients with rupture before and during labor(P ＞ 0.05). However，the rates of complete uterine rupture(26.19% ，11.11%)，massive blood transfusion(16.67%，11.11%)and hospitalization costs(11 576.33 RMB，14 846.30 RMB)were lower than those of postpartum group (63.16%，68.42%，25 310.57 RMB，P ＜ 0.05). Conclusion：In this study，the clinical manifestations of uterine rupture were mainly characterized as abdominal pain，abnormal fetal heart rate or vaginal bleeding，and some patients had no specific clinical manifestations. Non⁃scar uterine rupture，especially if detected late，may result in a more severe adverse outcome.