Objective：This study aims to explore the prognostic value of chemokine CCL2(C -C motif)in bronchoalveolar lavage fluid(BALF)and gender-age-physiological index(GAP)scores for idiopathic pulmonary fibrosis(IPF)in clinical practice and the correlation between them. Methods：Total 35 patients with IPF hospitalized in Nanjing Gulou Hospital from January 2017 to December 2019 were analyzed retrospectively. In the same period，10 outpatients with chronic cough(CC)but no other lung diseases or other organ diseases were collected. The differences of gender，age，percentage of predicted forced vital capacity(FVC%)，percentage of predicted diffusing capacity for carbon monoxide(DLCO%)(except CC group)，blood gas analysis and other indicators between the two groups were compared. At the same time，the level of CCL2 in serum and BALF was detected，and the differences of CCL2 level and survival time between different GAP groups and the correlation between CCL2 and GAP score were analyzed. Results：Compared with CC group，CCL2 in serum and BALF increased in IPF group. The comparison between IPF group(phase Ⅰ，Ⅱ and Ⅲ)and CC group showed that there were differences in oxygenation index，FVC%，CCL2 level in serum and BALF，and there were significant differences in DLCO% among IPF group(phase Ⅰ，Ⅱ and Ⅲ). In terms of correlation，CCL2 in BALF was negatively correlated with FVC% or DLCO%，and positively correlated with GAP score. The survival time of IPF group(stage Ⅰ，Ⅱ and Ⅲ)was different among the three groups. Conclusion：It is further verified in this stndy that CCL2 and GAP scores in BALF can predict the prognosis of IPF. At the same time，it is the first time to explore the differences of CCL2 level in BALF in different GAP stages，and there is a correlation between CCL2 and GAP scores in BALF.