Objective：This study aims to analyze the epidemiological characteristics of coronavirus disease 2019(COVID - 19) caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron variant and provide data support for prevention and control measures followed. Methods：The COVID-19 data during February 13，2022 to April 9，2022 were obtained from official website of Jiangsu Province Health Commission and municipal governments. Descriptive epidemiological methods were used to analyze the characteristics of cases. Results：As of April 9，2022，the spread of COVID - 19 caused by SARS - CoV - 2 Omicron variant in Jiangsu Province has been initially contained，with a cumulative incidence of 0.48/100 000 and a fatality rate of 0. It was characterized by a high proportion(76.3%)of asymptomatic patients，and most of the confirmed cases were mild. The median age was 42 years，and 16.9% infected individuals were under 20 years old. The median incubation period of Omicron BA.1 variant was 5.0(4.5，6.0)days，and that of BA.2 variant was 3.0(2.8，3.5)days，with significant difference(P＜0.05). There was a high proportion of cluster cases(81.6%). Among them，the main type was family cluster. Conclusion：Omicron variant is highly infectious，with short incubation period and weakened virulence. At this stage，the fatality rate of infection caused by Omicron variant in Jiangsu Province was 0. The results of precise epidemic control measures implemented in Jiangsu Province were remarkable.