Research progress of autophagy in adipose tissue affecting the pathogenesis of obesity
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R589.2

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    Abstract:

    Obesity is a chronic metabolic disease characterized by abnormal or excessive accumulation of adipose tissue,which is caused by an increase in adipocyte volume(hypertrophy)and number(hyperplasia). It is determined by environmental factors and genetic factors. In recent years,the roles of autophagy in regulating adipocyte number,adipogenesis,and white fat browning process have attracted extensive attention. This article systematically reviewed the effects of three different types of autophagy in adipose tissue on processes such as adipogenesis,white fat browning,and fat metabolism,aiming to clarify the effect of autophagy on adipose tissue function and obesity,and then provide potential targets for obesity prevention and treatment.

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季学涛,张许,刘谨,李仲.脂肪组织中自噬影响肥胖发病机制的研究进展[J].南京医科大学学报(自然科学版英文版),2023,(2):275-282.

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  • Online: February 16,2023
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