Parkinson’s disease（PD）is a neurodegenerative disease with complex pathogenesis and variable clinical manifestations. However，there are still many challenges in the pathogenesis and early diagnosis. Recently，positron emission tomography -magnetic resonance（PET/MR）has emerged as a truly multi - modal imaging tool，which can precisely extract and combine physiological and metabolic information in different time and space，thereby enrich imaging basis for the research of PD from molecular level to clinical diagnosis and treatment.