Uterine malignant tumors mainly include cervical cancer and endometrial cancer，which are the second and third most common female malignant tumors in China，respectively. The mortality of uterine malignant tumors is increasing by years，and the patients tend to be younger. In order to achieve individualized and accurate treatment，accurate staging of uterine lesions and high - quality therapeutic evaluation are needed. Positron emission tomography（PET）imaging of uterine malignant tumors，including glucose metabolism，cell proliferation，estrogen receptor，somatostatin receptor，hypoxia imaging and fibroblast activation protein inhibitor imaging，has significant advantages in tumor staging，monitoring response to targeted therapy，and early identification of chemoradiotherapy resistance. It has become a hot research topic in diagnosis and treatment of cervical and endometrial cancer.