The meninges,a four-layer membrane-like enclosure around the central nervous system(CNS),house a significant population of immune cells and is an important barrier and pathway for entering the CNS;however,the specific immune processes remain elusive. Recent identification of meningeal lymphatic vessels has shed light on the involvement of meninges in metabolite clearance,immune surveillance and response. Here,we provide a comprehensive review of advancements in meningeal immunity research and its implications for associated disorders. Additionally,potential avenues for future investigations in the realm of meningeal immunity are suggested.
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SUN Peng, GAO Junying. Research progress on of the meningeal immunity in central nervous system diseases[J].,2024,(3):398-409.