Association between carotid intima⁃media thickness and subclinical left ventricular systolic function
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R540.45;R540.48

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    Abstract:

    Objective:To explore the relationship between carotid intima -media thickness(cIMT)and subclinical left ventricular function in population of Danyang community. Methods:The study subjects were recruited in 2021 from the Station Community of Danyang City,Jiangsu Province. cIMT was measured and analyzed by GE Vivid E90 ultrasound instrument. Two-dimensional(2D) speckle tracking technology was used to collect left ventricular global longitudinal strain(LVGLS)of the left ventricle as an indicator for assessing subclinical systolic function. The e’and E/e’ratio were obtained from mitral valve blood flow spectra and tissue Doppler imaging,serving as indicators for evaluating subclinical diastolic function. Results:A total of 561 participants with an average age of (58.2 ± 11.7)years were enrolled,among whom 339(60.4% )were females. Using tertiles of cIMT as a categorical variable,in univariate analysis,LVGLS,E/A ratio,and e’decreased as cIMT tertiles increased,while the E/e’ratio increased(all Ptrend ≤ 0.002), except for left ventricular ejection fraction. However,after further multivariate adjustment,only LVGLS continued to decrease with increasing cIMT tertiles(P < 0.05). Continuous variable analysis after natural logarithm transformation of cIMT yielded results similar to categorical variable analysis,with only LVGLS showing a significant negative correlation with cIMT(r=- 0.087,P=0.041),and similar findings were observed in regression analysis(β =- 1.12,P=0.041). Conclusion:In the Danyang community population in Jiangsu,increased cIMT is independently correlated with decreased GLS.

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李一博,张雪,梁君雅,花木莲,张思奇,高云,陈超,赵熙璇,何姗姗,王新月,周天娜,何安霞,刘鸣.颈动脉内中膜厚度与亚临床左心室收缩功能的关系[J].南京医科大学学报(自然科学版英文版),2024,(4):491-498,510.

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  • Received:November 19,2023
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  • Online: April 11,2024
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