Association between carotid intima⁃media thickness and subclinical left ventricular systolic function
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R540.45;R540.48

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    Abstract:

    Objective:To explore the relationship between carotid intima -media thickness(cIMT)and subclinical left ventricular function in population of Danyang community. Methods:The study subjects were recruited in 2021 from the Station Community of Danyang City,Jiangsu Province. cIMT was measured and analyzed by GE Vivid E90 ultrasound instrument. Two-dimensional(2D) speckle tracking technology was used to collect left ventricular global longitudinal strain(LVGLS)of the left ventricle as an indicator for assessing subclinical systolic function. The e’and E/e’ratio were obtained from mitral valve blood flow spectra and tissue Doppler imaging,serving as indicators for evaluating subclinical diastolic function. Results:A total of 561 participants with an average age of (58.2 ± 11.7)years were enrolled,among whom 339(60.4% )were females. Using tertiles of cIMT as a categorical variable,in univariate analysis,LVGLS,E/A ratio,and e’decreased as cIMT tertiles increased,while the E/e’ratio increased(all Ptrend ≤ 0.002), except for left ventricular ejection fraction. However,after further multivariate adjustment,only LVGLS continued to decrease with increasing cIMT tertiles(P < 0.05). Continuous variable analysis after natural logarithm transformation of cIMT yielded results similar to categorical variable analysis,with only LVGLS showing a significant negative correlation with cIMT(r=- 0.087,P=0.041),and similar findings were observed in regression analysis(β =- 1.12,P=0.041). Conclusion:In the Danyang community population in Jiangsu,increased cIMT is independently correlated with decreased GLS.

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LI Yibo, ZHANG Xue, LIANG Junya, HUA Mulian, ZHANG Siqi, GAO Yun, CHEN Chao, ZHAO Xixuan, HE Shanshan, WANG Xinyue, ZHOU Tianna, HE Anxia, LIU Ming. Association between carotid intima⁃media thickness and subclinical left ventricular systolic function[J].,2024,(4):491-498,510.

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History
  • Received:November 19,2023
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  • Online: April 11,2024
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