A prospective cohort study on the relationship between metabolic syndrome and its components and the incidence of stroke
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1.Department of Chronic Disease,Wujin District Center for Disease Control and Prevention,Changzhou 213164 ; 2.School of Public Health,Nanjing Medical University,Nanjing 211166 ,China

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R589;R743

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    Abstract:

    Objective:To investigate the association between metabolic syndrome(MS)and its components with the risk of stroke incidence. Methods:A prospective cohort study was conducted to compare the differences in demographic information,behavioral lifestyle,dietary habits,medical history,and MS - related indicators between people with and without stroke. The Cox proportional hazards regression analysis model was used to analyze the association between MS components,their interactions,and the incidence of stroke. Results:Stroke patients had higher age,waist circumference(WC),body mass index(BMI),blood pressure(BP),total cholesterol(TC),triglycerides(TG),and fasting plasma glucose(FPG)compared to non - stroke patients. After adjusting for confounding factors,MS,WC,TG,BP,and FPG were all associated with an increased risk of stroke,with abnormal BP showing the strongest association with stroke incidence. There were no multiplicative interaction or additive interactions between WC,TG,BP,and FPG. Conclusion:MS is associated with an increased risk of stroke incidence. WC,TG,BP,and FPG independently contribute to stroke risk,with abnormal BP exerting the greatest impact on stroke incidence.

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孔晓玲,史宏,潘英姿,许敏锐,石素逸,宗菁,闫于飘,杨佳成,张锡炳,杭栋,刘逸舒,强德仁.代谢综合征及其组分与脑卒中发病关系的前瞻性队列研究[J].南京医科大学学报(自然科学版英文版),2024,(9):1238-1245.

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History
  • Received:April 30,2024
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  • Online: September 13,2024
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