A prospective cohort study on the relationship between metabolic syndrome and its components and the incidence of stroke
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1.Department of Chronic Disease,Wujin District Center for Disease Control and Prevention,Changzhou 213164 ; 2.School of Public Health,Nanjing Medical University,Nanjing 211166 ,China

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R589;R743

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    Abstract:

    Objective:To investigate the association between metabolic syndrome(MS)and its components with the risk of stroke incidence. Methods:A prospective cohort study was conducted to compare the differences in demographic information,behavioral lifestyle,dietary habits,medical history,and MS - related indicators between people with and without stroke. The Cox proportional hazards regression analysis model was used to analyze the association between MS components,their interactions,and the incidence of stroke. Results:Stroke patients had higher age,waist circumference(WC),body mass index(BMI),blood pressure(BP),total cholesterol(TC),triglycerides(TG),and fasting plasma glucose(FPG)compared to non - stroke patients. After adjusting for confounding factors,MS,WC,TG,BP,and FPG were all associated with an increased risk of stroke,with abnormal BP showing the strongest association with stroke incidence. There were no multiplicative interaction or additive interactions between WC,TG,BP,and FPG. Conclusion:MS is associated with an increased risk of stroke incidence. WC,TG,BP,and FPG independently contribute to stroke risk,with abnormal BP exerting the greatest impact on stroke incidence.

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KONG Xiaoling, SHI Hong, PAN Yingzi, XU Minrui, SHI Suyi, ZONG Jing, YAN Yupiao, YANG Jiacheng, ZHANG Xibing, HANG Dong, LIU Yishu, QIANG Deren. A prospective cohort study on the relationship between metabolic syndrome and its components and the incidence of stroke[J].,2024,(9):1238-1245.

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History
  • Received:April 30,2024
  • Revised:
  • Adopted:
  • Online: September 13,2024
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