Objective：To evaluate the relationship between pregnancy and the growth of ground glass nodules（GGNs）through a single-center retrospective cohort analysis. Methods：Clinical and radiologic data of 44 pregnant women who underwent pre-and post- pregnancy chest CT scans due to pulmonary GGNs were retrospectively reviewed. Based on imaging characteristics，the GGNs were divided into the pure GGNs（PGGNs），heterogeneous GGNs（HGGNs），and part solid nodules（PSN）. The size of a GGN was determined as the maximum diameter in axial chest CT images，and the observation interval was the time between pre - and post - pregnancy chest CT scans. Growth of a GGN was defined as an increase of 2 mm in the maximum diameter，an increase of 2 mm in the solid composnent，or the appearance of new solid component. Results：Among the 44 pregnant women，70 GGNs were detected， including 66 PGGNs and 4 HGGNs. Of these，43 GGNs had a diameter of ＜ 6 mm，22 were between 6.0 and 7.9 mm，4 were between 8.0 and 9.9 mm，and 1 GGN was ≥10 mm. No growth of pulmonary GGNs was observed at a median observing interval of 779 days （ranging from 337 to 2 795 days）. Conclusion：Pregnancy is unlikely to cause the growth of pulmonary PGGNs with a small diameter. Therefore，women of child-bearing age who plan to become pregnant need not be overly concerned about the growth of such GGNs.