Aim To explore the relationship between carotid intima-media thickness (cIMT) and subclinical left ventricular function in population of Danyang community. Methods The study subjects were recruited in the Station Community of Danyang City, Jiangsu Province in 2021. The carotid intima-media thickness (cIMT) was analyzed and measured by GE Vivid E90 ultrasound instrument. 2D speckle tracking, mitral flow spectrum and tissue Doppler imaging collected global longitudinal strain (GLS), as indicator of subclinical systolic function, and e’ as well as E/ e’ ratio, as markers of subclinical diastolic function, respectively. Results A total of 561 participants (mean age = 58.2 ± 11.7 years) were enrolled, including 339 females (60.4%). cIMT was analyzed as a categorical variable using the tertile method. In simple categorical analyses, GLS (20.5%, 20.2% and 19.8%)，E/A ratio (1.13, 0.92 and 0.79) and e’ (10.0, 8.6 and 7.6 cm/s) all decreased from tertiles 1 to 3 of cIMT, while E/e’ ratio (7.5, 8.2 and 8.9) increased from tertiles 1 to 3 of cIMT (P ≤ 0.002) except for left ventricular ejection fraction (P = 0.207). However, after further adjusting for confounding factors, only GLS significantly decreased across tertile of cIMT groups (P < 0.05). Further analysis was conducted using Logarithmic transforming cIMT as a continuous variable, and the results were similar to those of the categorical variable analysis, significantly negative association were only observed between GLS and natural log-transformed cIMT (β = -1.12; P = 0.04). Conclusion In community-dwelled population in Danyang County, increased cIMT is independently correlated with decreased GLS.