Objective To evaluate the efficiency of video laparoscopic surgery in endometriosis and infertility. Methods Fifty-nine women with endometriosis or infertility from our department were treated. Intervention(s): The video laparoscopic operations included adhesiolysis, coagulating small endometriosis implants, removal or partial removal endometriosis cyst or opening endometriosis cyst and coagulating cystic liner, oophorectomy. For infertility, adhesiolysis of distal fallopian tube, expending of fimbria or salpingostomy or fimbrioplasty were performed. Tubal patency was confirmed at laparoscopy by observation of the passage of methylene blue from vagiua through the fimbrial openings of the tubes. Results 20 patients with endometriosis after operations were follow up (2 to 27 months), symptoms disappeared or significant improved in 12 of 15 patients who had dysmenorrhea previously and 3 patients no any change. There were no recurrences after operations in 7 patients with removed endometrial cysts. The seven of 17 patients in endometriosis and infertility had pregnancies after operations between the period from 1 to 7 month. Ten patients of 20 patients with infertility have pregnancies after operations. There was no severe complications. Only 2 patients had omalgia and one had acute pelvic infection one week after operation through coitus. Two patients received laparotomy. Conclusion Video laparoscopic surgeries are suitable for treatment of endometriosis and infertility.