Objective：To research the method of establishing subsiding model of avascular necrosis of femoral head. Methods： Femoral heads were frozen by liquid nitrogen, and the blood vessel and parenchyma of fundus were destroyed. X-ray and histology examination were made periodically after operation to evaluate osteo necrosis and the subsequent repair. Results：Necrosis of the femoral head was confirmed by histology in the thirty week、the seventh week and the eleventh week after operation, but repairing is not obvious. Radiographic evidence and gross observation showed Necrosis of the femoral head, but obvious subsiding appeared in the eleventh week. Conclusion：The typical animal subsiding model of avascular necrosis of the femoral head can be established with blood vessel destroy and liquid nitrogen freezing.