Objective:To explore the relationship between the circumstances of intra and extra cranial artery stenosis and the risk factors with ischemic cerebrovascular disease. Methods:347 patients were performed by using DSA, which were divided into young middle aged and old aged group by different age and the cerebrovascular stenosis(CVS) and non-stenosis(CVNS) group by with or without stenosis. Statistical analysis was used to evaluate the incidence, degree, distribution and risk factors of intra and extra cranial artery stenosis. Results:The prevalence of intra and extra cranial artery stenosis in ischemic cerebrovascular disease group is 152/347(43.8%). The frequency of stenosis of intracranial artery was 80/152(52.6%). The frequency of stenosis of extracranial artery was 21/152(13.8%). The frequency of stenosis of intracranial and extracranial artery was 51/152(33.6%). The degree of intra and extra cranial artery stenosis was positively correlated to the age(rs=0.156,P < 0.05). Hypertension(HBP),diabetes(DB),homocysteic(HCY),total cholesterol(TC),fibrin(FIB), in CVS group were significantly higher than that in CVNS group(P < 0.05). Conclusion: The incidence of stenosis of intracranial artery is higher than that of extracranial artery with cerebral artery stenosis of ischemic cerebrovascular disease. The distribution of cerebral artery stenosis correlated with age.The level of HBP, DB, HCY, TC and FIB was positively correlated to the rate of carotid artery stenosis.