Objective:To investigate foveal architecture after routine retinal detachment surgery for macular-off retinal detachment(RD) and analyze the correlation of it and visual acuity. Methods:41 eyes of 41 patients with macular-off RD underwent best-corrected visual acuity(BCVA) measurement and optical coherence tomography(OCT) scan through the fovea before surgery and 1 week,1,3,6,12 months after surgery. Statistical analysis of the data was performed. Results:1 week after surgery, BCVA was 0.05~0.50(P = 0.019), and 41.5 percent of patients showed subfoveal fluid reduction on OCT(P = 0.008). At 1 month, there was no obvious change on BCVA(P = 0.084) and subfoveal fluid(P = 0.053). At 3 month, the average BCVA was 0.1~0.6, which improved above 2 lines was 75.6%. At 12 months, the average BCVA was 0.15~1.00, which improved above 2 lines was 92.7%, and subfoveal fluid was absorbed completely in 95.1% patients. There was statistic different between group of 12 months after surgery and 6 months after surgery(P = 0.0019). Conclusion:Infra-clinical foveal detachment could be detected in the patients with successful retinal reattachment surgery by OCT examination. It could provide the forecast for visual acuity prognosis of the patients with macular-off retinal detachment.