Objective:To evaluate the effect of inhibiting scar formation and safety of reforming viscocanalostomy with absorbable and non-absorbable pericardial patch implantation. Methods:18 New Zealand white rabbits were equally divided into three groups as experimental groups A,B and control group C. One piece of non-absorbable pericardial patch was implanted into each eye of group A while absorbable one into each eye of group B.Nothing was implanted in group C during reforming viscocanalostomy. Internal structures and lasting time of the scleral space are observed. Results:The formed filter blebs lasted longer in group A and B than group C. The pathology process showed that the spaces in sclera of group A and B were remained while scar formation was found in control group at the twelfth week. Conclusion:Implantation of absorbable and non-absorbable pericardial patches in reforming viscocanalostomy is safe and effective that can inhibit scar formation. Reaction caused by absorbable pericardial patches is lighter than that of non-absorbable ones. Absorbable pericardial patches may lead to better result in inhibiting scar formation.
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ZHANG Wei-zhong, YUAN Zhi-lan, YU Yan, YANG Qin, CHEN Qin, HONG Jin, SHUAI Jie. Experimental studies of Reforming viscocanalostomy with new implantation materials imp-lanted in rabbit eyes[J].,2007,(12):1444-1446.