Study on the relationship between the stenosis of coronary and left ventricular cardiac function
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    Abstract:

    Objective:To investigate the correlation between the stenosis degree of coronary and the left ventricular cardiac dysfunction. Methods:The coronary stenosis degree were analyzed retrospectively on 117 patients(male 91,female 26) by angiography. The parameters of blood pressure,serum lipid and echocardiography were observed. According to Gensini’s score, the correlation between the stenosis degree of coronary and cardiac dysfunction were analyzed. Results:When Gensini’s score level was examined as a categorical variable ordering by quartile values. There were significant differences in diastolic blood pressure(DBP)(P = 0.019),left atrial dimension(LAD)(P = 0.003),left ventricular end diastolic dimension(LVDd)(P = 0.000),left ventricular end systolic dimension(LVDs)(P = 0.000), fraction shortening(FS)(P = 0.001), left ventricular ejection fraction(LVEF)(P = 0.000) and HDL-C(P = 0.016) among the groups with different Gensini’s scores. Compared Gensini’s scores with Spearman, Gensini’s score was positively correlated with LAD(R = 0.341,P = 0.000),LVDd(R = 0.373,P = 0.000) and LVDs(R = 0.399,P = 0.000),respectively. Gensini’s score was negatively correlated with FS(R = -0.298,P = 0.001),LVEF(R = -0.320,P = 0.000) and HDL-C(R = -0.276,P = 0.003). By the multiple linear regression between the Gensini’s score and paramenters,LVDs and DBP were independently associated with the scores of the stenosis degree of coronary. LVDs and DBP were independently associated with Gensini’s score. Conclusion:LVEF and FS were negatively correlated with the stenosis degree of coronary and independent from other tradiovascular risk factors.

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鲁 晶,王连生,贾恩志,雍永宏,王 晖,朱铁兵,杨志健,许 迪,陈 莉.冠状动脉狭窄程度与左心功能的相关性研究[J].南京医科大学学报(自然科学版英文版),2008,28(8):1007-1010.

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  • Received:November 27,2007
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