Impact of the metabolic syndrome on cardiac function in a Chinese population
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    Abstract:

    Objective:To investigate the association of the diagnostic components of metabolic syndrome(MS) with the cardiac function in Chinese. Methods:In 843 subjects recruited in Zhejiang province,we measured each participant’s body height,body weight,waist and hip circumferences,and blood pressure. The observers were administered a standardized questionnaire to collect information on smoking habits,alcohol consumption and use of antihypertensive drugs. Echocardiography was performed on each subject according to the recommendations of the American Society of Echocardiography for the measurements of LVEF,E/A ratio,DTE,and Tei index. Venous blood was sampled for biochemical measurements. Results:843 subjects included 288(34.2%) women,and 191(22.7%) hypertensive patients,of whom 82(42.9%) took antihypertensive drugs. Compared to subjects in normal group,MS patients had significiantly lower LVEF(P = 0.049) and E/A ratio(P < 0.001),and higher DTE(P < 0.001) and Tei index(P < 0.001). Moreover,LVEF and E/A ratio decreased,and DTE and Tei index increased, with the number of MS components. Conclusion:The number of MS-diagnosis components was associated with the impairment of cardiac function.

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张 毅,许 迪,李 燕,李利华,王继光.代谢综合征及其诊断组分对心脏功能的影响[J].南京医科大学学报(自然科学版英文版),2008,28(8):1015-.

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  • Received:February 20,2008
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