Objective:Compared with the porcelain-fused metal restorations,the study is to evaluate the alteration of color on CAD/CAM alumina glass-infiltrated composite with different color Vita α veneering porcelain,helping the color-selecting and color-matching in clinical practice. Methods:Four groups of CAD/CAM alumina glass-infiltrated composite(ALC) and ten porcelain-fused Ni-Cr alloys specimens(randomized into two groups) were routinely layered with A2/A3 opaque-dentine porcelain,dentine porcelain and enamel porcelain. The resulting color differences were measured and calculated. Results:There were significant color differences in four groups of ALC,two groups of porcelain-fused Ni-Cr alloys specimens and also between the experimental and control groups(P < 0.01). Conclusion:The color space of alumina self-made glass-infiltrated composite was in the range of Chinese teeth chroma. Compared with the porcelain-fused metal restorations,the color of ALC was shifted to the lightness and yellow in b*-axis,which corresponded with the characteristics of Chinese teeth.